Corpus overview


MeSH Disease

Human Phenotype


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    Retroperitoneal Hemorrhage MESHD During Veno-Venous Extracorporeal Membrane Oxygenation in COVID-19 Patientss: Clinical Experience and Review of Literature

    Authors: Jingchen Zhang; Xujian He; Jia Hu; Tong Li

    doi:10.21203/ Date: 2020-05-30 Source: ResearchSquare

    Background: Retroperitoneal hemorrhage MESHD is a rare and severe complication in patients undergoing extracorporeal membrane oxygenation (ECMO). Retroperitoneal hematoma MESHD after the operation of multiple ECMO in a single center at the same time is extremely rare. The causes and treatment options can provide clinical experience and bring some inspiration.Case presentation: Three cases of retroperitoneal hemorrhage MESHD patients with Corona Virus Disease MESHD-19 (COVID-19) are introduced; they had respiratory failure HP and were treated with veno-venous ECMO or veno-arterial-venous ECMO. Retroperitoneal hemorrhage MESHD occurred during ECMO treatment. Among the three cases, 2 cases were found due to abdominal pain MESHD abdominal pain HP, and 1 case was found because of a decrease in ECMO circuit flow rate and hemoglobin level. 2 cases were treated with transcatheter arterial embolization, and 1 case was treated conservatively. The hemorrhage MESHD in each of the 3 cases did not deteriorate. Through early diagnosis and treatment, satisfactory treatment results were achieved for these 3 patients.Conclusions: During the period of ECMO treatment, there is a low incidence of retroperitoneal hematoma MESHD, yet it comes with a high risk. This is due to anticoagulant use and some local mechanical injuries. If a decline in blood SERO flow velocity and hemoglobin is detected, retroperitoneal hematoma MESHD should be taken into consideration, and early aggressive therapy should be started.

    Placental pathology in COVID-19

    Authors: Elisheva D Shanes; Leena B Mithal; Sebastian Otero; Hooman A Azad; Emily S Miller; Jeffery A Goldstein

    doi:10.1101/2020.05.08.20093229 Date: 2020-05-12 Source: medRxiv

    Objectives: To describe histopathologic findings in the placentas of women with COVID-19 during pregnancy. Methods: Pregnant women with COVID-19 delivering between March 18, 2020 and May 5, 2020 were identified. Placentas were examined and compared to historical controls and women with placental evaluation for a history of melanoma MESHD melanoma HP. Results: 16 placentas from patients with SARS-CoV-2 were examined (15 with live birth in the 3rd trimester 1 delivered in the 2nd trimester after intrauterine fetal demise). Compared to controls, third trimester placentas were significantly more likely to show at least one feature of maternal vascular malperfusion (MVM), including abnormal or injured maternal vessels, as well as delayed villous maturation, chorangiosis, and intervillous thrombi. Rates of acute and chronic inflammation MESHD were not increased. The placenta from the patient with intrauterine fetal demise showed villous edema MESHD edema HP and a retroplacental hematoma MESHD. Conclusions: Relative to controls, COVID-19 placentas show increased prevalence SERO of features of maternal vascular malperfusion (MVM), a pattern of placental injury reflecting abnormalities in oxygenation within the intervillous space associated with adverse perinatal outcomes. Only 1 COVID-19 patient was hypertensive despite the association of MVM with hypertensive disorders and preeclampsia HP. These changes may reflect a systemic inflammatory or hypercoagulable state influencing placental physiology.

    COVID-19 associated meningoencephalitis MESHD complicated with intracranial hemorrhage MESHD intracranial hemorrhage HP. A case report.

    Authors: Mohammad Alolama; Anas Rashid; Debora Garozzo

    doi:10.21203/ Date: 2020-05-10 Source: ResearchSquare

    Introduction: The Coronavirus pandemic that started in December 2019 is mainly related to clinical pictures consistent with respiratory symptoms; nevertheless, reports about neurological complications have recently appeared in the medical literature.The case: we describe a case of a 36 years old Coronavirus-positive patient that was admitted on emergency MESHD basis; his clinical presentation included neurological symptoms such as drowsiness HP and mild confusion MESHD confusion HP. Imaging revealed findings consistent with meningoencephalitis MESHD complicated by intracerebral hematoma and subdural MESHD hematoma MESHD. The latter was surgically evacuated after it became chronic and evidence of Coronavirus was found in the fluid.  Conclusion: our experience confirms that neurological complications might be a likely event in COVID-19. Although uncommon, the possible occurrence of meningoencephalitis MESHD should be kept in mind by physicians involved in the management of COVID-19 patients. Early recognition of brain involvement may provide better prognosis, preventing evolution into intracerebral hemorrhagic events.

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MeSH Disease
Human Phenotype

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