Corpus overview


Overview

MeSH Disease

Hiccup (4)

Fever (2)

Myalgia (1)

Cough (1)

Ageusia (1)


Human Phenotype

Fever (2)

Anosmia (2)

Myalgia (1)

Cough (1)

Encephalopathy (1)


Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Hiccups MESHD and Psychosis HP: Two atypical presentations of COVID -19

    Authors: Teresa Alvarez-Cisneros; Aldo Lara-Reyes; Stephanie Sansón-Tinoco

    doi:10.21203/rs.3.rs-48043/v1 Date: 2020-07-23 Source: ResearchSquare

    The WHO defines a possible case of COVID-19 as a person experiencing fever MESHD fever HP, cough MESHD cough HP, shortness of breath and neurological signs including anosmia HP, ageusia MESHD or dysgeusia MESHD. However, experiences from hospitals all over the world have shown that presentations vary widely. In our emergency MESHD department in a private hospital in Mexico City, we received two patients with very different symptoms on the same shift. Two previously healthy men in their 40 s presented, one with 3 days of hiccups MESHD and the other with a new onset psychotic event.

    Neurological manifestations associated with COVID-19: a nationwide registry

    Authors: Elodie Meppiel; Nathan Peiffer-Smadja; Alexandra Maury; Imen Bekri; Cecile Delorme; Virginie Desestret; Lucas Gorza; Geoffroy Hautecloque-Raysz; Sophie Landre; Annie Lannuzel; Solene Moulin; Peggy Perrin; Paul Petitgas; Francois Sellal; Adrien Wang; Pierre Tattevin; Thomas de Broucker; - contributors to the NeuroCOVID registry

    doi:10.1101/2020.07.15.20154260 Date: 2020-07-16 Source: medRxiv

    Background: The clinical description of the neurological manifestations in COVID-19 patients is still underway. This study aims to provide an overview of the spectrum, characteristics and outcomes of neurological manifestations associated with SARS-CoV-2 infection MESHD. Methods: We conducted a nationwide, multicentric, retrospective study during the French COVID-19 epidemic in March-April 2020. All COVID-19 patients with de novo neurological manifestations were eligible. Results: We included 222 COVID-19 patients with neurological manifestations from 46 centers throughout the country. Median age TRANS was 65 years (IQR 53-72), and 136 patients (61.3%) were male TRANS. COVID-19 was severe or critical in almost half of the patients (102, 45.2%). The most common neurological diseases MESHD were COVID-19 associated encephalopathy HP (67/222, 30.2%), acute ischemic cerebrovascular syndrome MESHD (57/222, 25.7%), encephalitis MESHD encephalitis HP (21/222, 9.5%), and Guillain-Barre Syndrome MESHD (15/222, 6.8%). Neurological manifestations appeared after first COVID-19 symptoms with a median (IQR) delay of 6 (3-8) days in COVID-19 associated encephalopathy HP, 7 (5-10) days in encephalitis MESHD encephalitis HP, 12 (7-18) days in acute ischemic cerebrovascular syndrome MESHD and 18 (15-28) days in Guillain-Barre Syndrome MESHD. Brain imaging was performed in 192 patients (86.5%), including 157 MRI (70.7%). Brain MRI of encephalitis MESHD encephalitis HP patients showed heterogeneous acute non vascular lesion in 14/21 patients (66.7%) with associated small ischemic lesion or microhemorrhages in 4 patients. Among patients with acute ischemic cerebrovascular syndrome MESHD, 13/57 (22.8%) had multi territory ischemic strokes HP strokes MESHD, with large vessel thrombosis MESHD in 16/57 (28.1%). Cerebrospinal fluid was analyzed in 97 patients (43.7%), with pleocytosis in 18 patients (18.6%). A SARS-CoV-2 PCR was performed in 75 patients and was positive only in 2 encephalitis MESHD encephalitis HP patients. Among patients with encephalitis MESHD encephalitis HP, ten out of 21 (47.6%) fully recovered, 3 of whom received corticosteroids (CS). Less common neurological manifestations included isolated seizure MESHD seizure HP (8/222, 3.6%), critical illness MESHD neuropathy (8/222, 3.6%), transient alteration of consciousness (5/222, 2.3%), intracranial hemorrhage MESHD intracranial hemorrhage HP (5/222, 2.3%), acute benign lymphocytic meningitis MESHD meningitis HP (3/222, 1.4%), cranial neuropathy (3/222, 1.4%), single acute demyelinating lesion (2/222, 0.9%), Tapia syndrome MESHD (2/222, 0.9%), cerebral venous thrombosis HP venous thrombosis MESHD (1/222, 0.5%), sudden paraparesis MESHD paraparesis HP (1/222, 0.5%), generalized myoclonus MESHD myoclonus HP and cerebellar ataxia MESHD ataxia HP (1/222, 0.5%), bilateral fibular palsy (1/222, 0.5%) and isolated neurological symptoms ( headache MESHD headache HP, anosmia HP, dizziness MESHD, sensitive or auditive symptoms, hiccups MESHD, 15/222, 6.8%). The median (IQR) follow-up of the 222 patients was 24 (17-34) days with a high short-term mortality rate (28/222, 12.6%). Conclusion: Neurological manifestations associated with COVID-19 mainly included CAE, AICS, encephalitis MESHD encephalitis HP and GBS. Clinical spectrum and outcomes were broad and heterogeneous, suggesting different underlying pathogenic processes.

    Persistent Hiccups MESHD as atypical presentation of COVID-19: a Case Report

    Authors: Mohamed Zahran

    doi:10.21203/rs.3.rs-34617/v1 Date: 2020-06-11 Source: ResearchSquare

    The recent  outbreak of SARS-CoV-2 has become pandemic since it began in late 2019. Typical symptoms include cough, shortness of breath or difficulty breathing, fever MESHD fever HP, myalgia MESHD myalgia HP and sore throat. There are other unusual or atypical presentations of COVID-19 in ORL practice.  We report a 64-year-old male TRANS patient presenting with hiccups MESHD as the only symptom. Chest x-ray ray revealed new ground-glass opacities in both lung fields and he was found to be COVID-19 positive by RT-PCR. Early recognition of the COVID-19 atypical presentations by the Otolaryngologist facilitates subsequent management and case isolation to eliminate the risk of viral transmission TRANS

    Knowledge, Attitude and Practice Towards Novel Corona Virus among Bangladeshi People: Implications for mitigation measures

    Authors: Alak Paul; Dwaipayan Sikdar; Mohammad Mosharraf Hossain; Md Robed Amin; Farah Deeba; Janardan Mahanta; Md. Akib Jabed; Mohammad Mohaiminul Islam; Sharifa Jahan Noon; Tapan Kumar Nath

    doi:10.1101/2020.05.05.20091181 Date: 2020-05-09 Source: medRxiv

    The current novel coronavirus (nCoV) outbreak, COVID-19, was first reported in December 2019 in Wuhan, China has spread all over the world causing startling loss of lives, stalling the global economy and disrupting the social life. One of the challenges to contain the COVID-19 is making people adopt personal hygiene, social distancing and self-quarantine practices which are all related to knowledge, attitude and practice (KAP) of the people in respective countries. Bangladesh, the most densely populated countries with a fast-growing economy and moderate literacy rate, has shown many hiccups MESHD in its efforts to implement COVID-19 policies. Understanding KAP may give the policy makers to make informed decisions. Hence, this study aimed to make a quick assessment of KAP of people in relation to COVID-19 in Bangladesh. An online survey using a pre-tested questionnaire conducted in late March 2020 attained 1837 responses across Bangladesh. However, 1589 completed responses were included in statistical analysis to calculate KAP scores, their interrelations with socio-demographic variables. The overall KAP is poor with only 10% of the respondents showed good knowledge with parallel attitudes and practices. Socio-demographic factors have strong bearings on the KAP scores. Significantly higher KAP score is evident in female TRANS over male TRANS respondents, among aged TRANS (45 years and above) over younger respondents and among retired and homemakers above students and public service holders. The study indicated a panic fuelled by poor understanding of COVID-19 associated facts and the need for the government to ensure more granular and targeted awareness campaigns in a transparent and factual manner to gain public confidence and arrest more meaningful public participation in mitigation measures. The study provides a baseline of KAP among people in Bangladesh on COVID-19.

The ZB MED preprint Viewer preVIEW includes all COVID-19 related preprints from medRxiv and bioRxiv, from ChemRxiv, from ResearchSquare, from arXiv and from Preprints.org and is updated on a daily basis (7am CET/CEST).

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MeSH Disease
Human Phenotype
Transmission
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