Corpus overview


Overview

MeSH Disease

Human Phenotype

Transmission

Seroprevalence

There are no seroprevalence terms in the subcorpus

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    Lessons Learned MESHD from the Early Stage of Convid-19 Pandemic: Clinical Analysis of 17 Related Deaths Associated with the 2019 Novel Coronavirus

    Authors: Cheng Zhang; Dandan Hong; Wenyue Chen; Qun Guan; Qingling Ren

    doi:10.21203/rs.3.rs-36607/v1 Date: 2020-06-19 Source: ResearchSquare

    Background Since the end of December 2019, a pneumonia HP pneumonia MESHD outbreak has occurred in Wuhan, Hubei Province, China. An epidemiological survey showed that the pneumovirus infection MESHD was closely related to the Huanan Seafood Wholesale Market in Wuhan, causing great panic among the general population. Through isolation of the pneumovirus strain and whole-genome sequencing, an infection MESHD model of the pneumovirus in human airway epithelial cells was established, and the pneumovirus was identified as the 2019 novel coronavirus (2019-nCoV), which belongs to the β-coronavirus genus. This study focused on the different characteristics of 2019-nCoV, which we learned at the early stage of Covid-19 pandemic will help us to save more lives during the outbreak. Methods The data of 17 deaths from 13 hospitals in Wuhan were obtained, and the initial symptoms, clinical features during the progression of the disease, and treatment processes were well analyzed. Results At the initial phase of the outbreak of 2019-nCoV, the lack of effective drugs for pneumonia HP pneumonia MESHD has led to lethal results in people who are often elderly TRANS with multiple underlying conditions. Males TRANS were affected more than females TRANS. Fever HP Fever MESHD, dry coughing HP, shortness of breath MESHD were the primary presentations, but not all. Chest images showed typical features of viral pneumonia MESHD pneumonia HP. Respiratory support treatment were needed, although sometimes did not improve respiratory distress HP. All the patients died of multiple organ failure MESHD caused by respiratory failure HP respiratory failure MESHD. Many treatments of covid-19 were done in ICU and lasted for a long time, the occupation of public medical resources will put pressure on the present medical system.Conclusions COVID-19 is different from pneumonia HP pneumonia MESHD caused by previous coronaviruses, it is more infectious and hard to manage. The initial death population were mainly elderly TRANS patients with underlying diseases. Protecting the elderly TRANS is an effective method to reduce the number of deaths. In the absence of nucleic acid detection reagents, relying on identifying typical symptoms and making full use of CT can increase the diagnosis of suspicious people. The condition of patients may deteriorate rapidly which increased the complexity of treatment. The increasing number of patients will put great pressure on the existing medical system.

    Clinical analysis of 17 deaths associated with the 2019 novel coronavirus

    Authors: cheng zhang; Dandan Hong; Wenyue Chen; Qingling Ren; Qun Guan

    doi:10.21203/rs.3.rs-24112/v1 Date: 2020-04-21 Source: ResearchSquare

    Background Since the end of December 2019, a pneumonia HP pneumonia MESHD outbreak has occurred in Wuhan, Hubei Province, China. An epidemiological survey showed that the pneumovirus infection MESHD was closely related to the Huanan Seafood Wholesale Market in Wuhan, causing great panic among the general population. Through the isolation and whole-genome sequencing of the pneumovirus, an infection MESHD model of the pneumovirus in human airway epithelial cells was established, and the pneumovirus was identified as the 2019 novel coronavirus (2019-nCoV), which belongs to the β-coronavirus genus. This study focus on lethiferous processes of infections associated with the new virus.Methods The data of 17 deaths from 13 hospitals in Wuhan were obtained, and the initial symptoms, clinical features during the progression of the disease, and treatment processes were well analyzed. Results At the early phase of the outbreak of 2019-nCoV, the lack of effective drugs for pneumonia HP pneumonia MESHD caused by the new coronavirus has led to lethal results in people who are often elderly TRANS with multiple diseases. Males TRANS were affected more than females TRANS. Fever HP Fever MESHD, dry coughing HP, shortness of breath MESHD are the primary presentations, but not all. Chest images showed viral pneumonia MESHD pneumonia HP. Symptomatic supportive treatment did not improve respiratory distress HP, leading to a sudden deterioration in the condition. The development of diseases are different from the other two cronoviruses.Conclusions Older people are at high risk of death MESHD due to 2019-nCoV infection MESHD, and protecting high-risk groups is an effective way to reduce the number of deaths. A large number of viral pneumonia HP pneumonia MESHD in Wuhan within a short period of time suggest the outbreak caused by a new virus, virus nucleic acid test will make accurate diagnosis, and the diagnosis based on clinical manifestations and imaging results provides a basis for early treatments.

The ZB MED preprint Viewer preVIEW includes all COVID-19 related preprints from medRxiv and bioRxiv, from ChemRxiv, from ResearchSquare, from arXiv and from Preprints.org and is updated on a daily basis (7am CET/CEST).
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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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