Corpus overview


MeSH Disease

Human Phenotype


There are no transmission terms in the subcorpus


There are no seroprevalence terms in the subcorpus

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    Mononeuritis multiplex MESHD: an unexpectedly common feature of severe COVID-19

    Authors: Edward Needham; Virginia Newcombe; Andrew Michell; Rachel Thornton; Andrew Grainger; Fahim Anwar; Elizabeth Warburton; David Menon; Monica Trivedi; Stephen Sawcer

    doi:10.1101/2020.07.19.20149898 Date: 2020-07-28 Source: medRxiv

    The prolonged mechanical ventilation required by patients with severe COVID-19 is expected to result in significant Intensive Care Unit - Acquired Weakness (ICUAW) in many of the survivors. However, in our post-COVID-19 follow up clinic we have found that, as well as the anticipated global weakness related to loss of muscle mass, a significant proportion of these patients also have disabling focal neurological deficits MESHD relating to an axonal mononeuritis multiplex MESHD. Amongst the 69 patients with severe COVID-19 that have been discharged from the intensive care units in our hospital, we have seen 11 individuals (16%) with such neuropathies MESHD. In many instances, the multi-focal nature of the weakness MESHD in these patients was initially unrecognised as symptoms were wrongly assumed to simply relate to "critical illness neuropathy MESHD". While mononeuropathy HP mononeuropathy MESHD is well recognised as an occasional complication of intensive care, our experience suggests that such deficits MESHD are common and frequently disabling in patients recovering from COVID-19.

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MeSH Disease
Human Phenotype

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