Corpus overview


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MeSH Disease

Human Phenotype

Pneumonia (1)


Transmission

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Seroprevalence

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    Role of pulmonary circulation assessment in CT imaging in evaluating the severity and tendency of severe and critical COVID-19 pneumonia HP pneumonia MESHD

    Authors: Qiongjie Hu; Yiwen liu; Yueying Pan; Ziyan Sun; Min Xiang; Kaiyan li; Liming Xia; huilan Zhang; Hanxiong Guan

    doi:10.21203/rs.3.rs-32243/v1 Date: 2020-05-28 Source: ResearchSquare

    Objective: To investigate the value of changes of pulmonary circulation in CT imaging in evaluating the severity and tendency of 2019 novel coronavirus disease MESHD (COVID-19) pneumonia HP pneumonia MESHD.Methods: This retrospective study analyzed 99 severe and critical COVID-19 pneumonia HP pneumonia MESHD patients including the 47 improved cases and 52 dead cases. Demographic data, laboratory findings, comorbidities, and CT imaging features including the diameters of pulmonary vein (PV), pulmonary artery MESHD ( PA MESHD) and ascending aorta were collected and assessed.Results: The PV diameters of the deceased patients were larger than recovered patients in the severe phase. Compared with the severe phase in the improvement group, the diameters of the pulmonary veins during the improved phase were smaller, and the total CT scores were significantly decreased (p < 0.001). Instead, there was no significant difference in the ratio of main PA MESHD to aorta diameter between the recovered group and the deceased group, nor did the self control of the recovered group and the deceased group (p > 0.05). Construction of a ROC curve yielded an optimal cut-off value of the PV diameters for prediction of survival (p < 0.05).Conclusion: The changes of the PV diameters might indirectly reflect the activity of pulmonary inflammation MESHD and cardiac insufficiency MESHD. Pulmonary manifestations of severe and critical COVID-19 pneumonia HP pneumonia MESHD might be related to myocardial injury MESHD and cardiac insufficiency MESHD, expecially accompanied by dilated PVs. Evaluation of changes in pulmonary circulation by chest CT images may be considered as a useful tool for determining the severity, fatal outcome and tendency of COVID-19.Key words: COVID-19, pneumonia HP pneumonia MESHD, pulmonary circulation MESHD, Computed Tomography

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MeSH Disease
Human Phenotype
Transmission
Seroprevalence


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